Respiratory Ailments

Pneumonia remains a significant global health concern, causing millions of deaths annually across all age groups. In 2016, it was responsible for approximately 3 million deaths worldwide, making it the fourth leading cause of death globally. Children under the age of five are particularly vulnerable. In 2019, pneumonia claimed the lives of over 700,000 children in this age group, accounting for 14% of all deaths among children under five. The elderly population is also at high risk. Between 1990 and 2019, deaths among individuals aged 70 and older increased from around 600,000 to over 1 million, largely due to a growing and aging population. These statistics highlight the critical need for effective strategies via early detection in real time & increasing accessibility to the underserved population globally. TimBre is poised to revolutionize the solution for this problem.

Tuberculosis (TB) remains a leading cause of death worldwide. In 2023, it was responsible for approximately 1.25 million deaths, including 161,000 among people living with HIV. This marks a slight decrease from the 1.32 million TB deaths reported in 2022. Despite this reduction, TB has likely returned to being the world’s leading cause of death from a single infectious agent, surpassing COVID-19. The global burden of TB remains significant, with an estimated 10.8 million people falling ill with the disease in 2023.

COPD rose by 86%, from approximately 8.7 million to 16.2 million new cases annually between 1990 and 2019. During 2019, North America reported the highest age-standardized incidence rate at 2,445.90 per 100,000 population as compared to lower rates in Europe and Asia. In 2019, the global prevalence of COPD was estimated at 10.3%, equating to approximately 391.9 million cases among individuals aged 30–79 years. Projections indicate that by 2050, the number of people with COPD could rise to around 645.6 million, representing a 36% increase from 2020 figures. COPD remains a leading cause of death worldwide, accounting for 3.5 million deaths in 2021, which is approximately 5% of all global deaths.

Lung Cancer remains a significant global health challenge, with incidence rates varying across regions and demographics. In 2022, there were approximately 2,480,675 new cases of lung cancer worldwide, accounting for 12.4% of all cancer diagnoses. In 2018, there were an estimated 2.1 million new cases of lung cancer globally. Lung cancer cases are expected to rise significantly by 2050, with both incidence and mortality projected to increase by more than 87% compared to 2022 figures.

TimBre™ is uniquely positioned to solve early detection of respiratory ailments by offering non-invasive, point of care and a real time modality that can be used from the comfort of one’s home or office any number of times.